Freakonomics Radio
Freakonomics Radio

671. Why Has There Been So Little Progress on Alzheimer’s Disease?

Apr 17, 2026 · 1h 1m

One possibility: a leading hypothesis pursued by researchers (and funders) was built on science that now appears to be fraudulent. Stephen Dubner speaks with the scientist and the journalist who blew the whistle. SOURCES: Charles Piller , investigative journalist for Science, author of Doctored . Matthew Schrag , associate professor of neurology at Vanderbilt University Medical Center. RESOURCES: Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's , by Charles Piller (2025). " The brain makes a lot …

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