E whakaatu ana anake
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S… Speaker 1 (Teaser Trailer)
Hello guys!
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S… Speaker 1 (Teaser Trailer)
Super excited to announce that Day Zero to Breakthrough is back for Season 2!
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S… Speaker 1 (Teaser Trailer)
This year the team is trying the pressure test again and this time
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they're trying to build a vaccine against the canine coronavirus.
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Very excited to share that Eva will be taking over from
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me as our host.
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S… Speaker 2 (Teaser Trailer)
Hello everyone!
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S… Speaker 2 (Teaser Trailer)
I can't wait to show you guys what's going on inside this Australian lab as
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S… Speaker 2 (Teaser Trailer)
they make this vaccine in less than 100 days and I hope you'll join me for the journey.
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S… Speaker 1 (Teaser Trailer)
So last year,
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they finished the pressure test in 186 days.
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S… Speaker 1 (Teaser Trailer)
So in about six months,
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S… Speaker 1 (Teaser Trailer)
they went from a sequence of DNA to a vaccine
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S… Speaker 1 (Teaser Trailer)
that was hypothetically ready to move into clinical trials,
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S… Speaker 1 (Teaser Trailer)
which is a huge achievement,
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but it's a long way off from the goal that CEPI has of 100 days.
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S… Speaker 1 (Teaser Trailer)
So this year I'm really excited to see them smash the 186 days
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S… Speaker 1 (Teaser Trailer)
and do it much faster,
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which I'm really optimistic that they will do because now they know the things they
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need to get done and the timeframes that those things take.
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So they should be able to be a lot more efficient this year.
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S… Speaker 1 (Teaser Trailer)
But the problem they had was because no one's ever done this assay before,
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S… Speaker 1 (Teaser Trailer)
right? This virus,
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the virus they were working on was very...
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knew and not researched a lot.
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S… Speaker 1 (Teaser Trailer)
So they didn't have a way of verifying whether their negative result in the assay was
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S… Speaker 1 (Teaser Trailer)
because the vaccine didn't work or because the assay itself hadn't been
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optimized properly.
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S… Speaker 1 (Teaser Trailer)
And so that meant that was a major obstacle in the progress of
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S… Speaker 1 (Teaser Trailer)
the pressure test last year.
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S… Speaker 1 (Teaser Trailer)
So I'm really excited this year.
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S… Speaker 1 (Teaser Trailer)
I hope that they're able to perfect that neutralization assay and see
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S… Speaker 1 (Teaser Trailer)
a successful result.
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S… Speaker 1 (Teaser Trailer)
That would be super exciting.
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S… Speaker 2 (Teaser Trailer)
Tune in next week to see the first video as we take you inside the start of their journey and
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S… Speaker 2 (Teaser Trailer)
hopefully you'll be able to follow along for the rest of it.

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