Voice 260603_195446 Rachel Meeting

Jun 04, 2026 05:10 · 1:45:08 · English · Whisper Turbo · 3 Munyori
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Lecture Index
Kuratidza chete
1:22
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So for
1:38
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
my presentation,
1:39
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
I will write both
1:43
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
PI's name or how to write.
1:46
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
I'm still confused.
1:47
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
For the presentation.
1:56
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Let me ask Jennifer tomorrow but I think I will be because they are
2:00
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
just for paperwork.
2:02
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Should I write or didn't
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
need to write?
2:09
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
I think just use my name.
2:11
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Just confirm then I will add one or two or maybe.
2:15
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Let
2:19
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
me ask Jennifer but I think this should be my name.
2:24
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
I don't have any problem,
2:25
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
yeah, but because for the official documentation,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
when I need to send them a proposal or other things,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
then I maybe follow a official way.
2:34
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Yeah, official maybe also.
2:36
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Yeah, yeah,
2:37
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
so that's why I must.
2:39
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Okay.
2:39
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
And,
2:42
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
you know,
2:45
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
I have to, I have to update that.
2:47
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
So what's the problem?
2:48
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
It'll be really busy today.
2:49
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
I didn't, it's okay.
2:50
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So,
2:51
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
what's the reason why,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
like, you cannot?
2:55
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
assigned for my contract oh because um a
2:59
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
couple years ago we had a uh mba student
3:03
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
and then um she's actually from belize
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
oh yeah and then she woke up dmc
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
one newton's and uh okay so one
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
day she came to my office and say uh so she
3:20
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
got she told me she married
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
and then had a baby girl but one
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
day she came to my office say her
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
husband abused her then
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
she need me go with her to the police office
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
and then so
3:45
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
we fired everything and then next day her
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
husband report the police say
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
with my other student steal,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
stole chemical,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
toxic chemical,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
want to poison her husband.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
And then I was investigated by
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
the police.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
And then we,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
and then at that time she was in fifth year.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So I asked her to graduate.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Well, I just met her graduate without publication.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So then I had a punishment.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
But now the regulation is already...
4:29
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
I think right after that year,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
the restriction
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
is not there.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
They cancelled it.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
The MBAs cancelled it.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So theoretically I'm not regulated by that but then
4:51
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
the committee say because she gradiate the
4:56
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
under in the years that the regulations
5:02
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
It's not unified.
5:03
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
I know,
5:03
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
I know.
5:04
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
And then,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
yeah,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
so that's the reason.
5:07
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
That's the reason.
5:10
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
So then,
5:11
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
actually,
5:12
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
well,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
I'm also working on that manuscript.
5:16
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
And then the other thing is that we repeated it.
5:20
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
So then she graduated without publication.
5:23
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
And then we repeated some of the experiment.
5:26
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
And then the result is different,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
quite different.
5:30
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
So I asked Shejie to pretty
5:35
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
much repeat everything.
5:36
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
So that takes a few years.
5:38
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Until her
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
publications.
5:44
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
But then the plan is this year you guys
5:48
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
should be transferred,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
I mean officially under my name.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
I don't know this
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
story.
5:56
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Yeah, yeah, yeah.
5:57
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
So that's the story.
6:01
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Okay,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
so I have to agree
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
that I still do it some time for the ants.
6:09
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
But can you show me?
6:11
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
You want to show me something,
6:12
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
right? But it's
6:19
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
all about me.
6:19
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Okay.
6:20
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
But it is the same thing.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Oh,
6:23
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
okay.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Because I just want to
6:28
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
add some aims here.
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
I'm sorry.
6:37
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Okay, so what do you what
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
do you think about those genes that you Well,
6:45
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
the genes that you found specific present,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
the SNP specific present in the CM2.
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Yeah,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
how you can dig into that?
6:57
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Sorry,
6:59
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
I discovered.
7:01
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
No, no, that's all right.
7:03
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So, yeah,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
so I just think again to make some story.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So now I just integrate the genes and
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
the chromatin,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
the DNA methylation also
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
inside the presentation.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Okay.
7:18
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So I just want to show.
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
The DNA methylation.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Yeah, DNA methylation.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
this is just simple thing like the cross over
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
so I make it simple I just move all the things yeah so
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
because I thought maybe because there is a no need for the hit and model here
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
because later when we have a preliminary data then I will introduce the
7:40
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
hit and then how it's course and a lot loading because it's
7:44
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
just third slide or fourth slide if I get here so maybe it's too complicated
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
this is simple thing
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
easy to explain then later when they have a consultant right so yeah
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
yeah so logic is one thing floor is another thing and they layer
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
so you wanna you know have like big picture and zoom in here and
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
then so if you have like a complicated picture and then tell everything
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
then people will get confused and distracted like
8:13
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
today
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
so maybe i can play here so it's just step by step so you
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
can understand so i put here okay okay unknown yeah okay yeah
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
it is unknown not clear yes so uh the bottlenecks we are
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
how can we discuss that uh i have the mutant analysis limitation here and
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
yeah these are two here i just combine two and four here
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
myotic window and then i replace with the mutant limitation so
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
okay so after the mutant so
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Therefore, it's a key message and it's used to
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
connect one slide to another,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
like a story.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So after the bottlenecks,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
we discuss here.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Therefore,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
an ideal system should provide accessible meoside,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
predictable staging,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
visible chromosome,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
natural variation,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
strong chemical sources.
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
This is why we want to use the system.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Yes, the NAM system.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So the ideal system here we will discuss in the next slide.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So why it is considered.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So I just add here.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Nothing else.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So they have five that properties
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
that you put.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Yeah, so since scientists develop a mapping system using maze
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
lines, so they can study complex traits like crossover.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
It is like another thing
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
I just move or something I delete.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
And then from here,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
the mapping system I just linked here.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Then the mapping system,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
they just take the quantified line.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So, yes.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
I thought maybe I introduced B -SAMATRI later.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
That's fine.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Yeah, because they have a 15 line,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
they cross with B -73,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
and then they get a population.
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Do you have one slide or some information
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
to talk about the diversity of those lines?
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Like say...
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
What kind of diversity?
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
I mean, because this is really special within
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
the species.
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Most of the species,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
within the species,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
there's no such...
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
and there is one more option that I'm thinking maybe we didn't need
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
to introduce them F2 population because in our whole project now
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
we didn't touch we just touch F1 generation or maybe the
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
main one so yes maybe this we
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
could remove it
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
So you can put that in your...
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Supplement. Right.
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Unless when they ask you,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
what is nested association?
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Because this thing is a little complicated,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
like the 5 ,000 lines.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
And we didn't use anyone,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
and there is no role in whole slides.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So yeah,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
slide it.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Okay,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
so then I will introduce them to v730,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
because this system is based upon v730.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So all the annotations,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
like this is important for the input.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So then I will tell them that the
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
MAGE -9 population provide a common B73 framework.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So to study how natural effect complexity.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So this is important because this is based upon B73.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
I think it's okay.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
then I will introduce them about the Chasma because so we will I
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
will introduce them that
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Because all the 25 lines,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
so a lot of people working on that 25 lines,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
so there is one study.
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
There is only one study.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Only one study.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So yeah,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
I will introduce them about the jasma and then I will introduce them that there
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
is a three kind of method to study crossover.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
There is a sequencing,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
there is a markers and jasma and here you can look at jasma is very
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
difficult to study.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So that's why we choose to study the three.
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
And then you will also,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
not only difficult to study,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
you also want to point out the constraint.
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
For example,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
like it's not accurate.
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
And then,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
yeah,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
you're not going
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
to talk about crossover.
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Oh yeah,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
you did,
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
so then you can talk about this including crossover type 1 and
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
type 2.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Yes, yes.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So yeah,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
of course.
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S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
And we consider crossover type 1
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
is the...
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Yes.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So then we
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
just know about the phenotype.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
There's a lot of study gaps present here.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So the first thing is like what biological mechanism called reduction crossover for
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
machine. We don't know.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Like the comments that you give me I think the genetic
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
or genomic factor we don't know So
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
this is some kind of study gaps and
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
maybe the
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So then we will propose,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
to answer these questions,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
we will propose this hypothesis.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So this is like the broad hypothesis,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
which consists of all the aims that are here.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So it consists of natural variation,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
hybridization,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
and extradition.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Caused
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
by natural variation effecting class I variation.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So this is relevant to AIM.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
And natural variation AIM -2 and hybridization.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So then to answer this question,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
like to answer that hypothesis,
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
we have a series of aims.
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S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
One,
14:13
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
two, three.
14:14
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So now I write like this one.
14:16
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
This one is M1 and this one is hypothesis
14:21
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
for the M1.
14:21
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
This is just like then I split main hypothesis
14:25
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
into three hypotheses.
14:27
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So this can be alternative hypothesis.
14:29
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Or it's a,
14:32
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
okay,
14:33
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
reduce the other version defect.
14:36
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So this
14:41
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
can be used as alternative hypothesis.
14:42
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
But you need some...
14:47
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
evidence to you know because
14:52
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
this is reasonable yes based on
15:00
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
whatever you told me before but then this
15:05
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
hypothesis has sounds like come
15:09
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
from nowhere because because
15:14
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
I
15:19
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
think when you propose you probably don't need a I
15:23
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
don't I don't think you need a hypothesis for this
15:28
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
end because we have in our proposal we write hypothesis
15:32
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
for each end
15:37
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
You can have a rationale for each end but you don't necessarily
15:41
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
have a hypothesis for each end because some end is kind
15:46
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
of like this description or you know it's
15:50
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
not
16:00
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
We can propose like this one,
16:02
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
reduce cross,
16:02
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
like this supplanting.
16:04
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
What if,
16:07
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
let's say,
16:08
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
because hypothesis
16:13
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
is built on some evidence,
16:17
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
some facts or some observation.
16:20
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So this is the observation.
16:24
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
before we have the observation is far too.
16:27
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
And then this is,
16:29
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
we want to answer this question because the observation,
16:33
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
which is CM22A has lower crossover.
16:37
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So we want to know which step limited that.
16:40
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So that doesn't really make,
16:41
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
that makes sense a lot.
16:45
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
this to answer this doesn't really need a hypothesis
16:49
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
because this is a like a deeper observation so
16:53
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
once we have the
16:56
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Deeper observation then we can we can make a new
17:00
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
hypothesis or like never the hypothesis say oh why
17:04
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
the DSP is lower is it because the
17:09
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
genomics or is it because the genetic
17:13
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
so You can rephrase this but
17:17
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
not like a hypothesis per se because this sentence doesn't
17:22
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
you know make
17:25
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Sense.
17:25
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Sense,
17:26
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
yeah.
17:26
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So far,
17:29
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
it's all fine.
17:29
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
This is fine because
17:33
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
it is.
17:34
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
It does make sense,
17:36
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
right? Because,
17:37
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
yeah, it's a wild type and then it contains a lot of variation.
17:41
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
And then,
17:42
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
yeah.
17:43
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So this,
17:44
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
you can rephrase it.
17:46
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
It doesn't sound like...
17:47
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
High torches.
17:48
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Yeah.
17:49
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Maybe into one line,
17:50
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
just like the...
17:52
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Reduce crossover frequency in CML2 to affect the
17:56
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
class 1 crossover formation.
17:57
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Just like that one.
17:58
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Yeah, that's fine.
17:59
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
That's fine.
18:00
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Yeah. And for the second,
18:01
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
I am thinking about like include the word natural variation.
18:05
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Like the reduction in class 1 crossover formation is due to natural
18:09
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
variation.
18:09
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Like this.
18:11
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Or diversity.
18:11
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Yeah,
18:12
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
for the M2.
18:13
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
So this is just like the...
18:16
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
hypothesis one is not working hypothesis it's
18:21
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
not hypothesis but just like for
18:25
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
the formality and then for hybridization
18:29
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
yeah because they want I didn't understand because they
18:33
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
want you have a one main hypothesis then you need to
18:44
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
I understand she wants to
18:48
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
have a structure,
18:50
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
but it doesn't need
18:54
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
to be like that.
18:56
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
But you
19:03
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
can rephrase it.
19:03
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
You can
19:08
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
probably say it the other way.
19:17
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
First of all,
19:18
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
it's not defect because it's wild type,
19:21
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
so don't say defect.
19:22
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
It's result from LAS
19:26
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
-DSB or SC
19:31
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
constraint.
19:38
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
so you can rephrase it yeah then it's fine okay but it's not like
19:42
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
the result from defect because it's not defect and then and then this
19:47
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
is uh doesn't so deep so if it's a defect of sc
19:51
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
so it's like why how yeah
19:55
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
because we use the word may so maybe
20:00
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
we can turn it into the some kind of objective so because the purpose
20:04
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
of this is just to before starting the aim so they can be objective
20:09
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Yeah, so they can get some idea like what kind of analysis they are doing here.
20:12
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Right, what is that?
20:13
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
So, so,
20:13
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
exactly.
20:14
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
So then you can say,
20:15
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
so actually this is the bridge to introduce
20:20
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
we were going to...
20:21
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
I see.
20:22
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Right,
20:22
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
right, right.
20:23
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
And, yeah,
20:24
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
yeah. Because they will remember this one line because when you enter into
20:28
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
the AIM, you have a multiple analogy.
20:30
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Yeah, yeah, yeah.
20:30
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
So,
20:31
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
yeah, that's why my purpose is to introduce this one so they have
20:35
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
briefly idea what they are going to do.
20:38
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So maybe some kind of I will not specify it
20:42
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
like a hypothesis or objective just like We
20:47
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
want to test that things in here like just like in do
20:52
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
not I will not emphasize on the word hypothesis
21:00
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
It's not defect.
21:02
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
I mean,
21:03
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
synonym of defect is alter or what kind of other
21:07
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
word we can use instead of...
21:08
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Well...
21:15
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
There is one word,
21:16
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
alter.
21:17
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Alter.
21:18
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Yeah.
21:19
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Or
21:25
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
modify. Change.
21:28
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Change.
21:32
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Well,
21:34
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
so it's because...
21:37
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
I think modify is more...
21:39
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Modify.
21:40
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Yeah.
21:42
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Because, yeah,
21:43
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
because the gene in
21:47
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
the wild type,
21:48
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
I mean,
21:51
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
if we found some,
21:52
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
if we found a gene that
21:57
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
in CML228 make all this,
21:59
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
that gene is commodified.
22:00
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
This is a big confusion for people.
22:01
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
When I told my project to someone,
22:04
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
they think maybe CML228 is a mutant death.
22:07
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Ah,
22:08
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
yeah.
22:09
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Yeah, but it's a wild type.
22:11
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
so okay from a m1 so first i
22:16
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
i did not know the exact so i will check you will just say
22:20
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
yeah but i maybe i think 26 yeah but
22:24
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
you need to know but yeah i
22:29
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
just write it for my okay so we
22:33
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
will grow in academia so this
22:40
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
one is
22:41
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
all these things same so here i also because the first
22:45
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
this one is like in the starting phase so
22:51
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
we can also introduce them then we also told them that
22:55
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
we grow these funny things growth chamber so we can with the
22:59
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
same image we can deliver to the message so we concise so
23:03
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
then i will tell them about the length from
23:08
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
here because it's just like linking
23:11
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
This is not consistent but like standard.
23:14
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So then I will the low
23:18
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
total crossword phenotype of CML22 is known but does this reduction specifically
23:23
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
affect the major class one crossword.
23:25
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So this is our first connections line.
23:28
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
We already know that CML has low but it will
23:33
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
affect class one or no.
23:34
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So we want to test it.
23:38
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So we use Hayten and Mark as one site at
23:42
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Pacheteen and that allows cytological comparison of cross -over formation
23:46
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
among genotype.
23:47
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Maybe cross -over one formation.
23:48
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So then I will introduce them to that model.
23:52
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
This one Hayten.
23:54
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Because they have the free idea.
23:56
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So I will not go into detail.
23:58
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So they will get idea.
24:00
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
Double strand break and then I will more emphasize here.
24:06
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
In the start of the patch team,
24:08
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
they just made two corsons and make for the future
24:12
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
crossovers.
24:12
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
And this is like the simple one.
24:16
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
So they just...
24:17
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So from the zygoteen,
24:20
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
they become mature.
24:22
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
And then,
24:24
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
yes,
24:25
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
so this is like the introduction.
24:27
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
And then,
24:28
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
so...
24:29
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
We will test whether CML2 to show reduced class 1 designation,
24:33
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
which represents the major selection of myotic crossover in case.
24:36
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
And class 1 represent 85 % and then class
24:41
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
2 represent 15%.
24:42
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So we have a literature reference also here.
24:45
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So then I will just briefly introduce them how we perform
24:50
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
this.
24:50
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
And then I will introduce this.
24:54
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
So,
24:56
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
oh,
24:57
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
there is one update.
25:01
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
There are two things.
25:03
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
One is that I just do the MI tracks
25:07
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
with the Squash method.
25:09
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
But I
25:14
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
use BFA.
25:15
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
What does it mean?
25:18
S… Speaker 2 (Voice 260603_195446 Rachel Meeting)
Is it everywhere or is it a lot of background?
25:25
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
There is one thing you can say background because in Squash the
25:30
S… Speaker 1 (Voice 260603_195446 Rachel Meeting)
antibody is just like background.

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