Video 1 v2 - Intro to Season 2
Aug 01, 2026 07:07
· 3:45
· English
· Whisper Turbo
· 2 Speakers
This transcript expires in 20 days.
Upgrade for permanent storage →
Showing only
0:00
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
Have you ever looked back at the COVID -19 lockdowns in 2020 and thought,
0:04
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
man,
0:04
man, that was a crazy year?
0:06
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
Within just a few months,
0:08
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
it felt like the whole world got flipped upside down because of COVID -19.
0:12
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
Well,
0:12
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
as crazy as it was for us at home,
0:15
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
re -watching The Office and learning to bake sandwich dough,
0:17
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
it was even more hectic vaccine labs all around the world as they
0:21
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
raced to make a vaccine against the clock.
0:24
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
Although vaccine development usually takes 10 to 15 years,
0:27
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
we managed to get the Pfizer and the Moderna vaccine in less than a year.
0:31
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
But why is that such an achievement?
0:33
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
What actually goes into making a vaccine?
0:36
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
And how can we be sure that if another pandemic threatens the world,
0:40
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
that we'll be ready with an effective vaccine even faster?
0:43
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
Hi, my name's Eva,
0:45
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
and in Season 2 of Day Zero to Breakthrough,
0:47
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
you'll come along with me as we take a look inside an Australian lab trying
0:52
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
to prove that they can make a vaccine in less than 100 days.
0:55
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
And don't worry,
0:56
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
you don't have to have watched Season 1 to be able to follow this one.
0:59
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
Right now,
1:00
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
I'm standing in front of the Australian Institute for Bioengineering and Nanotechnology,
1:04
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
where,
1:04
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
in 2022,
1:05
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
they developed a new kind of vaccine technology called CLAMP2.
1:09
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
CLAMP2 is a versatile base that can be quickly adapted to accommodate
1:13
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
all different kinds of viruses and generate a vaccine quickly.
1:16
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
If you're interested in how it works,
1:18
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
you can see more information about that here from last season.
1:21
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
Over the next 100 days,
1:22
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
the AIBN,
1:23
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
in collaboration with the Coalition of Epidemic Preparedness Innovations,
1:27
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
will be holding a pressure test to prove that they can create a vaccine that's
1:31
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
safe and effective in just 100 days.
1:33
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
This time,
1:34
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
they're trying to make a vaccine for canine coronavirus.
1:37
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
Yes,
1:38
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
so here in Keith's Chapel Group for the pressure
1:42
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
test, we have this moonshot aim of
1:47
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
developing a vaccine from sequence.
1:50
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
to, in theory,
1:51
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
emergency use in the shortest amount possible.
1:55
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
We learn from our previous experience and we are trying to improve in multiple
1:59
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
ways to be faster and better.
2:02
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
Last season,
2:03
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
they tried to make a vaccine for Chaparri Mamarino virus,
2:06
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
but they didn't quite succeed.
2:07
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
This time,
2:09
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
they've learned from their mistakes and what went wrong and their confidence in their abilities.
2:13
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
So from the first special test,
2:15
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
we learned that instead of relying on only one supplier,
2:18
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
raise different suppliers to see which ones can actually deliver
2:22
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
fastest.
2:23
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
And we are much more careful now about the timeline and
2:27
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
we feel all much more prepared and we know what we have to deliver by which
2:31
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
date. This particular protein,
2:34
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
it's larger,
2:34
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
so we'll have unique,
2:36
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
not challenges,
2:37
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
but differences when it comes to the length of processes like cloning
2:41
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
and...
2:43
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
In general,
2:44
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
it's been more difficult to handle,
2:45
S…
Speaker 2 (Video 1 v2 - Intro to Season 2)
but we are ready for it now.
2:48
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
On day one,
2:50
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
when I sat in on their first meeting,
2:51
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
in just a few hours,
2:53
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
the team had already figured out exactly what needed to be done.
2:55
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
Even though the genes and even some receptors for canine coronavirus have already
2:59
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
been described, that doesn't mean the team doesn't have any work cut out for them.
3:03
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
They still have to decide which parts of which genes to target for the vaccine.
3:07
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
That means analyzing the virus's genes and designing PCR primers.
3:11
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
These are small chunks of DNA that are used to bracket either end
3:15
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
of a target DNA sequence so that it can be copied or amplified into
3:19
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
much larger quantities that can be used to make the vaccine.
3:22
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
If you want to know more about this process,
3:24
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
then catch us next week when we do an episode on PCR.
3:26
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
Once these primers are designed,
3:28
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
they'll order these exact DNA sequences.
3:31
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
Once these arrive next week,
3:32
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
the team will start cloning the DNA,
3:34
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
and that's where we'll get to see the real science in action.
3:37
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
If you want to see what happens next,
3:39
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
subscribe to the channel and catch the rest of Season 2 on our journey to make a vaccine
3:43
S…
Speaker 1 (Video 1 v2 - Intro to Season 2)
in less than 100 days.
This transcript was generated by AI (automatic speech recognition). May contain errors — verify against the original audio for critical use. AI policy
Summary
Click Summarize to generate an AI summary of this transcript.
Summarizing...
Ask AI About This Transcript
Ask anything about this transcript — the AI will find relevant sections and answer.