5.2c Microcytic Anemias
ஒலிப்பேழைகள்
அத்தியாயங்கள்
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The last of the microcytic anemias would be due to thalassemia. Thalassemia is due to a decreased synthesis of globin chains. That's what we find in a thalassemia, that there's gonna be decreased production of globin chains. And so if there…
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5:02
And so if that person happens to receive another bad copy from, let's say, a parent, that would then result in the risk for severe anemia in offspring. So that's one important feature of the cyst deletion. The second important feature of th…
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7:17
Now, if four genes are deleted, then you've got a major problem, and it's going to express itself in the fetus, because remember that hemoglobin F, which was the hemoglobin in the fetus, contains alpha 2 and gamma 2. And so if there's no al…
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12:18அத்தியாயம் 4: So I would say when you think about beta thalassemia major, it's usually asymptomatic. 136s · Speaker 1
So I would say when you think about beta thalassemia major, it's usually asymptomatic. The patients have a microcytic hypochromic anemia with target cells. And then a key finding is an isolated or an independent increase in hemoglobin A2. A…
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14:35அத்தியாயம் 5: What do I mean by that? 289s · Speaker 2
What do I mean by that? Well, before you can understand massive erythroid hyperplasia, you need to recognize and remind yourself that usually erythropoiesis and hematopoiesis in particular erythropoiesis, occurs usually in the central axial…